Biotalys obtains a new fungicide resistance class for its first biofungicide

Evoca’s new mode of action is now officially listed as a new tool for growers to manage fungicide resistance

Ghent, Belgium, May 03, 2022 (GLOBE NEWSWIRE) — Press release

Biotalys (Euronext – BTLS), an agricultural technology (AgTech) company protecting crops and food with protein-based biocontrol solutions, today announces that the Fungicide Resistance Action Committee (FRAC) has granted an all-new class for the active ingredient of its first biofungicide, Evoca™*. This new classification, granted by an international panel of renowned technical experts, demonstrates to growers that Evoca will be a new tool that complements existing organic and conventional crop protection solutions to combat Botrytis fungal diseases and powdery mildew.

Evoca is an innovative protein-based biofungicide developed on Biotalys’ AGROBODY Foundry™ platform that helps control fungal diseases such as Botrytis and powdery mildew in fruits and vegetables. Evoca will provide growers with a new rotational partner in Integrated Pest Management (IPM) programs, reducing reliance on chemical pesticides. Demonstrating strong performance through more than 500 independent, company-led field and greenhouse trials across multiple regions, pathogens and crops, Evoca is expected to gain regulatory approval from the U.S. Environmental Protection Agency (EPA ) later this year.

Defined as a polypeptide in the recently released FRAC 2022 code list (under F10), Evoca’s bioactive was reclassified after providing extensive scientific evidence supporting its characteristics as a new mode of action targeting fungal pathogen membrane integrity, differentiating the bioactive from existing chemicals, microbials and plant extracts while providing a distinctive new tool to manage the development of pathogen resistance.

“Resistance to existing crop protection solutions continues to have a significant impact on growers’ ability to effectively protect crops and food, and the search for new modes of action is becoming more important than ever – especially for growers. complex and often devastating pathogens like Botrytis and powdery mildew,” mentioned Luc Maertens, COO of Biotalys. “Resistance has already developed for most available chemical fungicides targeting these diseases, and while most new products fall into existing categories, Evoca is in a new class of its own, giving growers a new tool in their toolbox to protect their crops.”

The FRAC is an international panel of industry experts, advising globally on best practices and the effectiveness of fungicides to limit crop loss, as fungicide resistance continues to be a major challenge. for farmers. FRAC members are recognized industry experts in the field of fungicide resistance. They are actively engaged in scientific work and discussion and frequently contribute to scientific symposia. The FRAC Mode of Action (MoA) classification provides growers, advisors, extensionists, consultants and crop protection professionals with a guide to selecting fungicides for use in an effective and sustainable fungicide resistance management strategy (for more information, see
“Over the past decade, very few fungicide products introduced to the market have achieved a whole new class of fungicide resistance like Evoca. The hard work and dedication of our team has resulted in further validation of our AGROBODY Foundry technology as a platform that can deliver new modes of action against major agricultural and food pathogens,” added Patrick SaddlesCEO of Biotalys. “Our protein-based biocontrols are designed to help close the current gaps in growers’ crop protection efforts and continue to lead the way into an era of safer and more sustainable food production.”

* Evoca™: recording pendingration. This product is currently not registered for sale or use in the United Statesthe European Union, or elsewhere and is not offered for sale.

About Biotalys

Biotalys is an agricultural technology (AgTech) company protecting crops and food with proprietary protein-based biocontrol solutions and aiming to provide alternatives to conventional chemical pesticides for a more sustainable and safer food supply. Based on its novel AGROBODY™ technology platform, Biotalys is developing a strong and diverse pipeline of effective product candidates with a favorable safety profile that aim to control major crop pests and diseases across the entire value chain, from floor to plate. Biotalys was founded in 2013 as a spin-off from VIB (Flanders Institute for Biotechnology) and has been listed on Euronext Brussels since July 2021. The company is based in the biotech cluster of Ghent, Belgium. More information on

For more information, please contact

Toon Musschoot, Head of IR & Communication
T: +32 (0)9 274 54 00
E: [email protected]

Important Notice

This announcement contains statements that are, or could be deemed to be, “forward-looking statements.” These forward-looking statements can be identified by the use of forward-looking terminology, including the words “aim”, “believe”, “estimate”, “anticipate”, “expect”, “intend”, ‘may’, ‘will’, ‘plan’, ‘continue’, ‘ongoing’, ‘possible’, ‘predict’, ‘plan’, ‘target’, ‘seek’, ‘would’ or ‘should’, and contain statements made by the company regarding the expected results of its strategy. By their nature, forward-looking statements involve risks and uncertainties, and readers are cautioned that none of these forward-looking statements offers any guarantee of future performance. The actual results of Biotalys may differ materially from those predicted by the forward-looking statements. Biotalys undertakes no obligation to release updates or adjustments to these forward-looking statements, except as required by law.

  • Press release – Biotalys obtains a new fungicide resistance class for its first biofungicide – May 3, 2022

  • Persbericht – Biotalys krijgt nieuwe resistentieklasse voor zijn eerste biofungicide – 3 May 2022

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